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4163-15-9

17-(cyclopropylmethyl)morphinan-3-ol synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: Et3N / CH2Cl2 / 14 h / Heating
2: LiAlH4 / tetrahydrofuran / 20 °C

References:

Neumeyer, John L.;Bidlack, Jean M.;Zong, Rushi;Bakthavachalam, Venkatesalu;Gao, Peng;Cohen, Dana J.;Negus, S. Stevens;Mello, Nancy K. [Journal of Medicinal Chemistry,2000,vol. 43,# 1,p. 114 - 122]