3-Piperidinecarboxylic acid, 3-(phenylMethyl)-, ethyl ester synthesis

2synthesis methods

Product Name:3-Piperidinecarboxylic acid, 3-(phenylMethyl)-, ethyl ester
CAS Number:170844-89-0
Molecular formula:C15H21NO2
Molecular Weight:247.33

71962-74-8 Synthesis

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3-Piperidinecarboxylic acid, 3-(phenylMethyl)-, ethyl ester

170844-89-0
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: CH₂Cl₂
2: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, -78 deg C, 2.) THF, from -78 deg C to 0 deg C
3: HCl / ethyl acetate

References:

Yang, Lihu;Morriello, Greg;Patchett, Arthur A.;Leung, Kwan;Jacks, Tom;Cheng, Kang;Schleim, Klaus D.;Feeney, William;Chan, Wanda W.-S.;Chiu, Shuet-Hing L.;Smith, Roy G. [Journal of Medicinal Chemistry,1998,vol. 41,# 14,p. 2439 - 2441]

3-BENZYL-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-ETHYL ESTER

170842-80-5
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170844-89-0
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References