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171925-27-2

1,2,7-Indolizinetriol, 8-aminooctahydro-, tribenzoate (ester), 1S-(1.alpha.,2.beta.,7.alpha.,8.alpha.,8a.alpha.)- synthesis

2synthesis methods
79831-76-8 Synthesis
CASTANOSPERMINE

79831-76-8
118 suppliers
$33.00/5mg

1,2,7-Indolizinetriol, 8-aminooctahydro-, tribenzoate (ester), 1S-(1.alpha.,2.beta.,7.alpha.,8.alpha.,8a.alpha.)-

171925-27-2
1 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) Bu2SnO, 3.) pyridine / 1.) MePh, reflux, 2 h, 2.) MePh, -70 deg C to room t., 3.) room t.
2: 1.) NaN3, 2.) H2 / 2.) 20percent Pd(OH)2/C / 1.) HMPT, 80 deg C, 2 h, 2.) EtOAc, EtOH, 24 h

References:

Furneaux, Richard H.;Gainsford, Graeme J.;Mason, Jennifer M.;Tyler, Peter C.;Hartley, Oliver;Winchester, Bryan G. [Tetrahedron,1995,vol. 51,# 46,p. 12611 - 12630]