Ethanone, 2,2,2-trifluoro-1-(4-methyl-2-thiazolyl)- (9CI) synthesis
1synthesis methods
- Product Name:Ethanone, 2,2,2-trifluoro-1-(4-methyl-2-thiazolyl)- (9CI)
- CAS Number:174824-73-8
- Molecular formula:C6H4F3NOS
- Molecular Weight:195.1623
Yield:174824-73-8 72%
Reaction Conditions:
Stage #1: 4-Methylthiazole;trifluoroacetic anhydride in toluene at -19;
Stage #2: with triethylamine in toluene at -19 - 20;Further stages.;
References:
Khodakovskiy, Pavel V.;Volochnyuk, Dmitriy M.;Panov, Dmitriy M.;Pervak, Igor I.;Zarudnitskii, Evgenij V.;Shishkin, Oleg V.;Yurchenko, Aleksandr A.;Shivanyuk, Alexander;Tolmachev, Andrey A. [Synthesis,2008,# 6,p. 948 - 956]