2-Cyclopenten-1-one, 4-hydroxy-2-(hydroxymethyl)-3-methyl- (9CI) synthesis

1synthesis methods

Product Name:2-Cyclopenten-1-one, 4-hydroxy-2-(hydroxymethyl)-3-methyl- (9CI)
CAS Number:176045-41-3
Molecular formula:C7H10O3
Molecular Weight:142.15

6,7-DIHYDRO-4H-CYCLOPENTA[1,3]DIOXIN-5-ONE

102306-78-5
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2-Cyclopenten-1-one, 4-hydroxy-2-(hydroxymethyl)-3-methyl- (9CI)

176045-41-3
1 suppliers
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) n-BuLi, diisopropylamine, HMPA, 2.) (+/-)-(10-camphorsulfonyl)oxaziridine / 1.) THF, -78 deg C, 1 h, 2.) THF, a) -78 deg C, 30 min, b) 0 deg C, 30 min
2: 2.) aq. HCl / 1.) THF, -78 deg C, 2 h

References:

Ohba, Masashi;Haneishi, Tsuyoshi;Fujii, Tozo [Chemical and Pharmaceutical Bulletin,1996,vol. 44,# 3,p. 525 - 529]