5-(Benzyloxy)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole synthesis
- Product Name:5-(Benzyloxy)-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
- CAS Number:176661-73-7
- Molecular formula:C20H20N2O
- Molecular Weight:304.39
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Yield:-
Steps:
5-benzyloxy-3-[1,2,5,6-tetrahydro-4-pyridinyl]-1H-indole
5-benzyloxy-3-[1,2,5,6-tetrahydro-4-pyridinyl]-1H-indole Starting with 5.0 gm (22 mMol) 5-benzyloxyindole and 6.88 gm (45 mMol) 4-piperidone.HCl.H2 O, 6.53 gm (97.6%) of 5-benzyloxy-3-[1,2,5,6-tetrahydro-4-pyridinyl]-1H-indole were recovered as a light yellow solid by the procedure described in Preparation I. The material was used in the subsequent step without further purification.
References:
Eli Lilly and Company US5521197, 1996, A
1215-59-4
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40064-34-4
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