(E)-3-(1-(tert-butoxycarbonyl)piperidin-4-yl)acrylic acid synthesis

4synthesis methods

Product Name:(E)-3-(1-(tert-butoxycarbonyl)piperidin-4-yl)acrylic acid
CAS Number:181073-79-0
Molecular formula:C13H21NO4
Molecular Weight:255.31

1-Piperidinecarboxylic acid, 4-(methoxymethylene)-, 1,1-dimethylethyl ester

138022-91-0
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(E)-3-(1-(tert-butoxycarbonyl)piperidin-4-yl)acrylic acid

181073-79-0
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: Acidic conditions; Heating
2: piperidine / pyridine / 70 °C

References:

Calvo, Raul R.;Meegalla, Sanath K.;Parks, Daniel J.;Parsons, William H.;Ballentine, Shelley K.;Lubin, Mary Lou;Schneider, Craig;Colburn, Raymond W.;Flores, Christopher M.;Player, Mark R. [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 5,p. 1903 - 1907]

154775-43-6 Synthesis

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181073-79-0
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References

141-82-2 Synthesis

141-82-2
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137076-22-3 Synthesis

1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

137076-22-3
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181073-79-0
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References

79099-07-3 Synthesis

79099-07-3
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181073-79-0
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References