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2,3-dihydro-5-hydroxy-3,3-diMethyl-1H-Isoindol-1-one synthesis

4synthesis methods
184906-29-4 Synthesis
5-Methoxy-3,3-diMethylisoindolin-1-one

184906-29-4
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Yield:184906-31-8 57%

Reaction Conditions:

with boron tribromide in dichloromethane;Ambient temperature;

References:

Fevig, Thomas L.;Bowen, S. Marc;Janowick, David A.;Jones, Bryan K.;Munson, H. Randall;Ohlweiler, David F.;Thomas, Craig E. [Journal of Medicinal Chemistry,1996,vol. 39,# 25,p. 4988 - 4996]