(S)-2-NITRO-6,7-DIHYDRO-5H-IMIDAZO[2,1-B][1,3]OXAZIN-6-OL synthesis
- Product Name:(S)-2-NITRO-6,7-DIHYDRO-5H-IMIDAZO[2,1-B][1,3]OXAZIN-6-OL
- CAS Number:187235-08-1
- Molecular formula:C6H7N3O4
- Molecular Weight:185.14
187235-06-9
2 suppliers
inquiry
187235-08-1
76 suppliers
$130.00/5mg
Yield: 86%
Reaction Conditions:
with hydrogenchloride in methanol;water at 60; for 4 h;Temperature;
Steps:
1 Example 1
17g of compound III, 6.3ml of 1M hydrochloric acid and 170ml of methanol were added to a 500ml reaction flask and reacted at 60°C for 4h.After the end, the solvent was evaporated to dryness, and the mixture was further added with methylene chloride. The mixture was filtered with suction and dried to give 10.10 g of compound IV as a pale yellow solid.86%.
References:
Ruiyang Pharmaceutical Co., Ltd.;Miao Dezu;Hu Qingwen;Li Lexiang;Yu Zhibo;Wang Hongguang;Zhu Xuwei CN107915747, 2018, A Location in patent:Paragraph 0039; 0043; 0054; 0060
187235-04-7
1 suppliers
inquiry
187235-08-1
76 suppliers
$130.00/5mg