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2-Propenoic acid, 3-(3-fluoro-4-methoxyphenyl)-, ethyl ester, (2E)- synthesis

4synthesis methods
-

Yield:187872-44-2 92%

Reaction Conditions:

in dichloromethane at 20 - 25; for 16 h;Inert atmosphere;

References:

West, Thomas H.;Walden, Daniel M.;Taylor, James E.;Brueckner, Alexander C.;Johnston, Ryne C.;Cheong, Paul Ha-Yeon;Lloyd-Jones, Guy C.;Smith, Andrew D. [Journal of the American Chemical Society,2017,vol. 139,# 12,p. 4366 - 4375] Location in patent:supporting information