Benzoic acid, 4-(3aS,4S,6R,6aR)-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-4H-1,3-dioxolo4,5-cpyrrol-4-yl- synthesis

3synthesis methods

Product Name:Benzoic acid, 4-(3aS,4S,6R,6aR)-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-4H-1,3-dioxolo4,5-cpyrrol-4-yl-
CAS Number:188744-88-9
Molecular formula:C21H33NO5Si
Molecular Weight:407.58

4H-1,3-Dioxolo4,5-cpyrrole, 4-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, (3aR,4R,6aS)-

153172-31-7
36 suppliers
inquiry

Benzoic acid, 4-(3aS,4S,6R,6aR)-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-4H-1,3-dioxolo4,5-cpyrrol-4-yl-

188744-88-9
1 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 4 steps
1: NCS / pentane / 0.5 h / Ambient temperature
2: 1.) BuLi, 2,2,6,6-tetramethylpiperidine / 1.) THF, 0 deg C, 2.) THF, -78 deg C
3: 55 percent / tetrahydrofuran / 1 h / -78 °C
4: 1.) BuLi / 1.) THF, -78 deg C, 1 h, 2.) -78 deg C to room temperature

References:

Furneaux, Richard H.;Limberg, Gerrit;Tyler, Peter C.;Schramm, Vern L. [Tetrahedron,1997,vol. 53,# 8,p. 2915 - 2930]

4H-1,3-Dioxolo4,5-cpyrrole, 4-(1,1-dimethylethyl)dimethylsilyloxymethyl-3a,6a-dihydro-2,2-dimethyl-, (3aR,4R,6aS)-

153172-33-9
7 suppliers
inquiry

188744-88-9
1 suppliers
inquiry

References

124-38-9
121 suppliers
$214.00/14L

4H-1,3-Dioxolo4,5-cpyrrole, 4-(4-bromophenyl)-6-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, (3aS,4S,6R,6aR)-

188744-83-4
1 suppliers
inquiry

188744-88-9
1 suppliers
inquiry

References