3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER synthesis

2synthesis methods

Product Name:3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER
CAS Number:191155-80-3
Molecular formula:C12H13F3O2
Molecular Weight:246.23

2-Propenoic acid, 3-[2-(trifluoromethyl)phenyl]-, ethyl ester, (2E)-

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3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID ETHYL ESTER

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Yield:191155-80-3 87.5%

Steps:

127.2 (2)

(2) Ethyl 3-(2-trifluoromethylphenyl)propanoate The object compound was obtained from ethyl (2E)-3-(2-trifluoromethylphenyl)propenoate as an oily substance, according to the similar manner to that of Example 125(2). yield: 87.5% ¹H-NMR (CDCl₃) δ; 1.25 (3H, t, J=7.2 Hz), 2.62 (2H, t, J=7.4 Hz), 3.14 (2H, t, J=7.4 Hz), 4.15 (2H, q, J=7.2 Hz), 7.27-7.65 (4H, m). IR (KBr) cm^-1; 1736, 1316, 1177, 1154, 1119, 1061, 1040, 758, 652.

References:

US2003/144338,2003,A1

392-83-6 Synthesis

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References