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2-(2-FLUORO-ETHOXY)-5-IODO-BENZOIC ACID METHYL ESTER synthesis

2synthesis methods
762-49-2 Synthesis
2-Fluoroethyl bromide

762-49-2
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4068-75-1 Synthesis
METHYL 5-IODOSALICYLATE

4068-75-1
117 suppliers
$13.00/1g

2-(2-FLUORO-ETHOXY)-5-IODO-BENZOIC ACID METHYL ESTER

193882-74-5
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Yield:193882-74-5 100%

Reaction Conditions:

with sodium hydride in tetrahydrofuran;mineral oil;Reflux;Inert atmosphere;

References:

Bai, Suping;Li, Shihong;Xu, Jinbin;Peng, Xin;Sai, Kiran;Chu, Wenhua;Tu, Zhude;Zeng, Chenbo;Mach, Robert H. [Journal of Medicinal Chemistry,2014,vol. 57,# 10,p. 4239 - 4251] Location in patent:supporting information

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