tert-butyl 4-(2-cyanophenyl)-5,6-dihydropyridine-1(2H)-carboxylate synthesis
- Product Name:tert-butyl 4-(2-cyanophenyl)-5,6-dihydropyridine-1(2H)-carboxylate
- CAS Number:194669-38-0
- Molecular formula:C17H20N2O2
- Molecular Weight:284.35
138647-49-1
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Yield:194669-38-0 97%
Reaction Conditions:
with tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran at 20; for 0.5 h;Arylation;
References:
Barrow, James C.;Nantermet, Philippe G.;Selnick, Harold G.;Glass, Kristen L.;Rittle, Kenneth E.;Gilbert, Kevin F.;Steele, Thomas G.;Homnick, Carl F.;Freidinger, Roger M.;Ransom, Rick W.;Kling, Paul;Reiss, Duane;Broten, Theodore P.;Schorn, Terry W.;Chang, Raymond S. L.;O'Malley, Stacey S.;Olah, Timothy V.;Ellis, Joan D.;Barrish, Andrea;Kassahun, Kelem;Leppert, Paula;Nagarathnam, Dhanapalan;Forray, Carlos [Journal of Medicinal Chemistry,2000,vol. 43,# 14,p. 2703 - 2718]