![](/CAS/GIF/195062-62-5.gif)
ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE synthesis
- Product Name:ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE
- CAS Number:195062-62-5
- Molecular formula:C15H21BO4
- Molecular Weight:276.14
![Methyl 4-iodobenzoate](/CAS/GIF/619-44-3.gif)
619-44-3
302 suppliers
$6.00/10g
![Pinacolborane](/CAS/GIF/25015-63-8.gif)
25015-63-8
218 suppliers
$22.39/5G
![ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE](/CAS/GIF/195062-62-5.gif)
195062-62-5
95 suppliers
$24.00/1g
Yield:-
Reaction Conditions:
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane at 85; for 16 h;
Steps:
13
EXAMPLE 13 Preparation of Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)Benzoate; [0105] EMI310.0[0106] A solution of methyl 4-iodobenzoate (2.00 g, 7.63 mmol) in 30 mL dioxane was degassed with Ar for 10 minutes. Then, Pd(dppf)Cl2 (171 mg, 3 mol %), triethylamine (3.27 mL), and pinacolborane (1.47 g, 11.45 mmol) were added. The resulting solution was stirred at 85[deg.] C. for 16 hours. The mixture was allowed to cool to ambient temperature, filtered through a pad of Celite(R), and concentrated in vacuo to obtain 3.97 g of product which was used without further purification. m/z=263 [M+H]<+>.
References:
Ladouceur, Gaetan H.;Schoen, William R.;Burke, Michael J. US2003/195352, 2003, A1 Location in patent:Page/Page column 34
![Benzocaine](/CAS/GIF/94-09-7.gif)
94-09-7
765 suppliers
$5.00/50mg
![Bis(pinacolato)diboron](/CAS/20180808/GIF/73183-34-3.gif)
73183-34-3
566 suppliers
$6.00/5g
![ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE](/CAS/GIF/195062-62-5.gif)
195062-62-5
95 suppliers
$24.00/1g
![Ethyl 4-bromobenzoate](/CAS/GIF/5798-75-4.gif)
5798-75-4
187 suppliers
$6.00/5g
![Bis(pinacolato)diboron](/CAS/20180808/GIF/73183-34-3.gif)
73183-34-3
566 suppliers
$6.00/5g
![ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE](/CAS/GIF/195062-62-5.gif)
195062-62-5
95 suppliers
$24.00/1g
![ETHYL 4-CHLOROBENZOATE](/CAS/GIF/7335-27-5.gif)
7335-27-5
127 suppliers
$10.00/1g
![Bis(pinacolato)diboron](/CAS/20180808/GIF/73183-34-3.gif)
73183-34-3
566 suppliers
$6.00/5g
![ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE](/CAS/GIF/195062-62-5.gif)
195062-62-5
95 suppliers
$24.00/1g
![Ethyl 4-iodobenzoate](/CAS/GIF/51934-41-9.gif)
51934-41-9
279 suppliers
$6.00/5g
![Bis(pinacolato)diboron](/CAS/20180808/GIF/73183-34-3.gif)
73183-34-3
566 suppliers
$6.00/5g
![ETHYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZOATE](/CAS/GIF/195062-62-5.gif)
195062-62-5
95 suppliers
$24.00/1g