ChemicalBook CAS DataBase List 2,3,4,5-Tetrahydro-8-(trifluoromethyl)-1H-pyrido[4,3-b]indole

2,3,4,5-Tetrahydro-8-(trifluoromethyl)-1H-pyrido[4,3-b]indole synthesis

2synthesis methods

Product Name:2,3,4,5-Tetrahydro-8-(trifluoromethyl)-1H-pyrido[4,3-b]indole
CAS Number:19735-44-5
Molecular formula:C12H11F3N2
Molecular Weight:240.22

41979-39-9 Synthesis

41979-39-9
115 suppliers
$15.00/10mg

2923-56-0 Synthesis

4-(Trifluoromethyl)phenylhydrazine hydrochloride

2923-56-0
177 suppliers
$8.00/5g

2,3,4,5-Tetrahydro-8-(trifluoromethyl)-1H-pyrido[4,3-b]indole

19735-44-5
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Yield:19735-44-5 66%

Reaction Conditions:

with boron trifluoride diethyl etherate;acetic acid at 20 - 90; for 2 h;Inert atmosphere;Fischer indole synthesis;

References:

Dossetter, Alexander G.;Beeley, Howard;Bowyer, Jonathan;Cook, Calum R.;Crawford, James J.;Finlayson, Jonathan E.;Heron, Nicola M.;Heyes, Christine;Highton, Adrian J.;Hudson, Julian A.;Jestel, Anja;Kenny, Peter W.;Krapp, Stephan;Martin, Scott;MacFaul, Philip A.;McGuire, Thomas M.;Gutierrez, Pablo Morentin;Morley, Andrew D.;Morris, Jeffrey J.;Page, Ken M.;Ribeiro, Lyn Rosenbrier;Sawney, Helen;Steinbacher, Stefan;Smith, Caroline;Vickers, Madeleine [Journal of Medicinal Chemistry,2012,vol. 55,# 14,p. 6363 - 6374] Location in patent:supporting information; experimental part

79099-07-3 Synthesis

79099-07-3
543 suppliers
$5.00/5g

368-90-1
155 suppliers
$15.00/1g

19735-44-5
16 suppliers
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References

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