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ChemicalBook CAS DataBase List 1H-Azepine-1,4-dicarboxylic acid, hexahydro-5-oxo-, 1,4-diethyl ester
19786-58-4

1H-Azepine-1,4-dicarboxylic acid, hexahydro-5-oxo-, 1,4-diethyl ester synthesis

2synthesis methods
-

Yield:19786-58-4 88.8%

Reaction Conditions:

with boron trifluoride diethyl etherate in diethyl ether at -30 - 20;

References:

Lyles-Eggleston;Altundas;Xia;Sikazwe;Fan;Yang;Li;Zhang;Zhu;Schmidt;Vanase-Frawley;Shrihkande;Villalobos;Borne;Ablordeppey [Journal of Medicinal Chemistry,2004,vol. 47,# 3,p. 497 - 508]