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1H-Imidazole, 1-(2-fluoro-4-nitrophenyl)- synthesis

1synthesis methods
-

Yield:154164-56-4 92%

Reaction Conditions:

with potassium carbonate in dimethyl sulfoxide at 90; for 18 h;Substitution;

References:

Genin, Michael J.;Allwine, Debra A.;Anderson, David J.;Barbachyn, Michael R.;Emmert, D. Edward;Garmon, Stuart A.;Graber, David R.;Grega, Kevin C.;Hester, Jackson B.;Hutchinson, Douglas K.;Morris, Joel;Reischer, Robert J.;Ford, Charles W.;Zurenko, Gary E.;Hamel, Judith C.;Schaadt, Ronda D.;Stapert, Douglas;Yagi, Betty H. [Journal of Medicinal Chemistry,2000,vol. 43,# 5,p. 953 - 970]