![](/CAS/GIF/38425-65-9.gif)
1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO- synthesis
- Product Name:1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-
- CAS Number:38425-65-9
- Molecular formula:C11H12O2
- Molecular Weight:176.21
![1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-, ETHYL ESTER](/CAS/GIF/22339-45-3.gif)
22339-45-3
23 suppliers
inquiry
![1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-](/CAS/GIF/38425-65-9.gif)
38425-65-9
35 suppliers
$45.00/100mg
Yield:38425-65-9 900 mg
Reaction Conditions:
with water;sodium hydroxide in methanol at 40; for 2 h;
Steps:
171.C
C. To a solution of ethyl 2-(2,3-dihydro-1H-inden-1-yl)acetate (1.1 g, 5.39 mmol) in CH3OH (20 mL) was added sodium hydroxide (0.65 g, 16.17 mmol) and H2O (2 mL). The reaction mixture was heated to 40 °C and stirred at that temperature for 2 h then was concentrated in vacuo.1M aqueous HCl (30 mL) was added to the reaction vessel and the resulting biphasic mixture was extracted with DCM (3 x 50 mL). The organic phase was washed with saturated aqueous NaCl (2 x 25 mL). The combined organics were dried over anhydrous Na2SO4, filtered and concentrated in vacuo to provide 2-(2,3-dihydro-1H-inden-1-yl)acetic acid (900 mg, 5.11 mmol) as a white solid.
References:
WO2018/26371,2018,A1 Location in patent:Paragraph 0127; 0303
![(3-oxo-indan-1-yl)-acetic acid](/CAS/20150408/GIF/25173-12-0.gif)
25173-12-0
28 suppliers
$99.70/50mg
![1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-](/CAS/GIF/38425-65-9.gif)
38425-65-9
35 suppliers
$45.00/100mg
![3-Phenylglutaric acid](/CAS/GIF/4165-96-2.gif)
4165-96-2
109 suppliers
$33.00/1g
![1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-](/CAS/GIF/38425-65-9.gif)
38425-65-9
35 suppliers
$45.00/100mg
![ethyl 2-(2,3-dihydro-1H-inden-1-ylidene)acetate](/CAS/20180808/GIF/28002-99-5.gif)
28002-99-5
4 suppliers
inquiry
![1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-](/CAS/GIF/38425-65-9.gif)
38425-65-9
35 suppliers
$45.00/100mg
![Carbon dioxide](/CAS/GIF/124-38-9.gif)
124-38-9
122 suppliers
$214.00/14L
![4-(2-BROMOPHENYL)-1-BUTENE 95](/CAS/GIF/71813-50-8.gif)
71813-50-8
22 suppliers
$336.95/1g
![1H-INDENE-1-ACETIC ACID, 2,3-DIHYDRO-](/CAS/GIF/38425-65-9.gif)
38425-65-9
35 suppliers
$45.00/100mg
![2-(3-BUTENYL)BENZOIC ACID](/CAS/GIF/89730-30-3.gif)
89730-30-3
11 suppliers
$252.00/1g