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ChemicalBook CAS DataBase List 1H-Indene-2-carboxylic acid

1H-Indene-2-carboxylic acid synthesis

11synthesis methods
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Yield:-

Steps:

198.A A.
A. Indene-2-carboxylic acid Indene (29.0g) is added to a solution of chlorosulfonylisocyanate (35.4g) in ether (75ml) with mechanical stirring. The mixture is vigorously stirred for 1 hour. The solid product is collected and washed with 1:1 ether/cyclohexane to give 48.2g of material, melting point 85°-88° C.

References:

E. R. Squibb & Sons, Inc. US4051248, 1977, A

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