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65060-93-7

1H-Pyrrole-2,5-dione, 3-bromo-1-methyl- synthesis

5synthesis methods
-

Yield:65060-93-7 100%

Reaction Conditions:

Stage #1: N-methylmaleimidewith bromine in diethyl ether; for 1 h;Reflux;
Stage #2: with triethylamine in diethyl ether at 0 - 18;

References:

Banwell, Martin G.;Jones, Matthew T.;Loong, David T.J.;Lupton, David W.;Pinkerton, David M.;Ray, Jayanta K.;Willis, Anthony C. [Tetrahedron,2010,vol. 66,# 47,p. 9252 - 9262] Location in patent:experimental part