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ChemicalBook CAS DataBase List (1R)-1-(4-FLUOROPHENYL)-2-METHYLPROPYLAMINE-HCl

(1R)-1-(4-FLUOROPHENYL)-2-METHYLPROPYLAMINE-HCl synthesis

2synthesis methods
Carbamic acid, N-[(1R)-1-(4-fluorophenyl)-2-methylpropyl]-, 1,1-dimethylethyl ester

1356862-11-7
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Yield:1213329-40-8 11.3 g

Reaction Conditions:

with hydrogenchloride in water;ethyl acetate at 20; for 16 h;Cooling with ice;

References:

Watanuki, Susumu;Matsuura, Keisuke;Tomura, Yuichi;Okada, Minoru;Okazaki, Toshio;Ohta, Mitsuaki;Tsukamoto, Shin-Ichi [Chemical and Pharmaceutical Bulletin,2011,vol. 59,# 11,p. 1376 - 1385] Location in patent:experimental part