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ChemicalBook CAS DataBase List [1S,2R]-trans-2-Aminocyclohexanol hydrochloride
13374-31-7

[1S,2R]-trans-2-Aminocyclohexanol hydrochloride synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: [((R,R)-3,5-t-Bu-salen)Co(III)(OTf)] / acetonitrile / 24 h / 50 °C
2: potassium hydroxide / ethanol; water / 20 h / 85 °C
3: hydrogenchloride / dichloromethane; diethyl ether; hexane

References:

Birrell, James A.;Jacobsen, Eric N. [Organic Letters,2013,vol. 15,# 12,p. 2895 - 2897]

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