(1S,6R)-3,7,7-Trimethylbicyclo[4.1.0]heptan-3α-ol synthesis
5synthesis methods
- Product Name:(1S,6R)-3,7,7-Trimethylbicyclo[4.1.0]heptan-3α-ol
- CAS Number:4017-79-2
- Molecular formula:C10H18O
- Molecular Weight:154.2493
Yield:4017-79-2 38 mg ，4017-92-9 12 mg
Reaction Conditions:
with iron(III)-acetylacetonate;methyl 4-nitrobenzenesulfonate;phenylsilane;sodium hydrogencarbonate in methanol at 0 - 20; for 12 h;Schlenk technique;Inert atmosphere;Overall yield = 64 percent; Overall yield = 50 mg; diastereoselective reaction;Reagent/catalyst;
References:
Bhunia, Anup;Bergander, Klaus;Daniliuc, Constantin Gabriel;Studer, Armido [Angewandte Chemie - International Edition,2021,vol. 60,# 15,p. 8313 - 8320][Angew. Chem.,2021,vol. 133,# 15,p. 8394 - 8401,8] Location in patent:supporting information