2-(1H-imidazol-1-yl)-5-nitropyridine synthesis
- Product Name:2-(1H-imidazol-1-yl)-5-nitropyridine
- CAS Number:23671-36-5
- Molecular formula:C8H6N4O2
- Molecular Weight:190.16
288-32-4
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4548-45-2
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$6.00/5g
23671-36-5
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$65.00/50mg
Yield:23671-36-5 87%
Reaction Conditions:
Stage #1: 1H-imidazolewith sodium hydride in N,N-dimethyl-formamide at 0; for 0.166667 h;Inert atmosphere;
Stage #2: 2-chloro-5-nitropyridine in N,N-dimethyl-formamide at 0 - 20;Inert atmosphere;
References:
McPhillie, Martin J.;Trowbridge, Rachel;Mariner, Katherine R.;O'Neill, Alex J.;Johnson, A. Peter;Chopra, Ian;Fishwick, Colin W. G. [ACS Medicinal Chemistry Letters,2011,vol. 2,# 10,p. 729 - 734] Location in patent:supporting information; experimental part
5418-51-9
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$12.72/1gm:
23671-36-5
22 suppliers
$65.00/50mg