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2-(2,2-DIFLUORO-PROPYLAMINO)-ETHANOL synthesis

1synthesis methods
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Yield:406-99-5 4.5 g

Reaction Conditions:

with lithium aluminium tetrahydride in diethyl ether;Reflux;

References:

Dow, Robert L.;Carpino, Philip A.;Hadcock, John R.;Black, Shawn C.;Iredale, Philip A.;DaSilva-Jardine, Paul;Schneider, Steven R.;Paight, Ernest S.;Griffith, David A.;Scott, Dennis O.;O'Connor, Rebecca E.;Nduaka, Chudy I. [Journal of Medicinal Chemistry,2009,vol. 52,# 9,p. 2652 - 2655] Location in patent:supporting information; experimental part

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