2,2,2-TRICHLOROETHYL ACETATE synthesis

8synthesis methods

Product Name:2,2,2-TRICHLOROETHYL ACETATE
CAS Number:625-24-1
Molecular formula:C4H5Cl3O2
Molecular Weight:191.44

108-05-4
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$4.00/1000g

115-20-8 Synthesis

115-20-8
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625-24-1
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$224.00/5ml-f

Yield: 100%

Reaction Conditions:

with dilithium tetra(tert-butyl)zincate in toluene at 0; for 1 h;Inert atmosphere;

Steps:

General procedure: A typical procedure was as follows. Vinyl acetate (5.0mmol), benzyl alcohol (1.0mmol), and solvent (2.0mL) were added to a glass ampoule which had been degassed and filled with nitrogen. A solution of TBZL (0.1mmol) in THF was added under a nitrogen atmosphere to the ampoule placed in a constant-temperature bath. Then the mixture was kept at 25 or 0°C and stirred. After a prescribed period, the mixture was diluted with CDCl₃ and transformed in a NMR tube. Conversion of the reaction was determined by ¹H NMR at 400MHz.

References:

Oshimura, Miyuki;Oda, Yuki;Kondoh, Keita;Hirano, Tomohiro;Ute, Koichi [Tetrahedron Letters,2016,vol. 57,# 19,p. 2070 - 2073]

115-20-8 Synthesis

115-20-8
278 suppliers
$8.00/25g

75-36-5 Synthesis