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[2-(2,3-dihydro-1H-indol-1-yl)phenyl]methanamine synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) NaH / 1.) DMSO, 1 h, 2.) DMSO, RT, overnight
2: 1.) borane-THF, 2.) 12 N HCl / 1.) THF, reflux, 1 h, 2.) THF, reflux, 1 h

References:

Glamkowski, Edward J.;Fortunato, James M.;Spaulding, Theodore C.;Wilker, Jeffrey C.;Ellis, Daniel B. [Journal of Medicinal Chemistry,1985,vol. 28,# 1,p. 66 - 73]