2-(2,4-DINITRO PHENYLTHIO) ACETIC ACID synthesis

6synthesis methods

Product Name:2-(2,4-DINITRO PHENYLTHIO) ACETIC ACID
CAS Number:32403-69-3
Molecular formula:C8H6N2O6S
Molecular Weight:258.21

68-11-1 Synthesis

68-11-1
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Yield:32403-69-3 74%

Reaction Conditions:

with triethylamine in 1,4-dioxane;water;

Steps:

7 2-(2,4-Dinitrophenylthio)-acetic acid

Example 7 2-(2,4-Dinitrophenylthio)-acetic acid Et₃N (1.5 g, 15 mmol) and mercapto-acetic acid (1 g, 11 mmol) were added to a solution of 1-chloro-2,4-dinitrobenzene (2.26 g, 10 mmol) in 1,4-dioxane (50 mL) at room temperature. After stirring at room temperature for 5 h, H₂O (100 mL) was added. The resulting suspension was extracted with ethyl acetate (100 mL*3). The ethyl acetate extract was washed with water and brine, dried over Na₂SO₄ and concentrated to give 2-(2,4-dinitrophenylthio)-acetic acid (2.3 g, 74%), which was used without further purification.

References:

US2011/98311,2011,A1 US2012/309758,2012,A1