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2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE synthesis

2synthesis methods
55646-01-0 Synthesis
2,2,5,7,8-PENTAMETHYLCHROMAN

55646-01-0
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2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE

161117-67-5
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: chlorosulfonuc acid / CH2Cl2 / 3.5 h / 0 - 20 °C
2: 28.1 g / ammonia / CH2Cl2 / 3 h / 0 °C

References:

Collins, Shawn K.;McDonald, Andrew I.;Overman, Larry E.;Rhee, Young Ho [Organic Letters,2004,vol. 6,# 8,p. 1253 - 1255]

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