2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE synthesis
- Product Name:2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE
- CAS Number:24038-68-4
- Molecular formula:C27H24O2
- Molecular Weight:380.48
Yield: 99%
Reaction Conditions:
with hydrogenchloride;3-mercaptopropionic acid in water at 80;Inert atmosphere;Reagent/catalyst;
Steps:
5 EXAMPLE 5
To a 3 necked reaction flask with nitrogen blanket equipped with condenser and overhead mechanical stirrer, 3 mol of 2-phenylphenol and 1 mol of acetone were added with concentrated HC1 followed by the addition of 600-1300 ppm (based on total reactant content) of 3-mercaptopropionic acid (3-MPA). The mixture was allowed to stir for 5 - 6 hours at 80°C giving good conversion and good selectivity (95%) towards PHP monomer. The crude product obtained was dissolved in dichloromethane and treated with aqueous 2N sodium hydroxide for approximately 30 minutes to provide the PHP sodium salt. The precipitated PHP salt was filtered then washed with organic solvent like ethylacetate, dichloromethane to remove excess 2-phenylphenol and other impurities. The sodium salt of PHP was dissolved in deionized water and acidified with iN HC1 to pH of 2 - 3, followed by 30 mins stirring. Precipitate formed was filtered and resulted in formation of more selective, more pure PHP monomer (>99%). Product was confirmed by ‘H NMR and purity was confimed by HPLC.
References:
SABIC GLOBAL TECHNOLOGIES B.V.;CHANDRA, Girish;SAIT, Meerakani Mohamed Ali;SHETTY, Sharankumar;TANWAR, Akhilesh WO2016/9359, 2016, A1 Location in patent:Paragraph 0065
90-43-7
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$10.00/5g
24038-68-4
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$28.00/5mg
