2-(2-CHLORO-PHENYL)-SUCCINIC ACID synthesis
- Product Name:2-(2-CHLORO-PHENYL)-SUCCINIC ACID
- CAS Number:6954-40-1
- Molecular formula:C10H9ClO4
- Molecular Weight:228.63
2856-63-5
336 suppliers
$17.00/10g
79-11-8
10 suppliers
$27.00/25g
6954-40-1
18 suppliers
$211.00/1g
Yield:6954-40-1 82.5%
Reaction Conditions:
Stage #1: chloroacetic acidwith potassium carbonate in N,N-dimethyl-formamide;
Stage #2: 2-Chlorophenylacetonitrilewith potassium hydroxide in N,N-dimethyl-formamide at 20 - 25; for 2 h;
Stage #3: with sodium hydroxide for 16 h;Heating;
References:
Makosza;Marcinowicz [Synthesis,2001,# 9,p. 1311 - 1312]
