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2-(2-Iodophenyl-d4)acetic Acid synthesis

1synthesis methods
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Yield:1217360-62-7 76.4%

Reaction Conditions:

Stage #1: 2H5-phenylacetic acidwith thallium(III) trifluoroacetate in trifluoroacetic acid-d1 at 20;
Stage #2: with potassium iodide in trifluoroacetic acid-d1;water; for 0.25 h;

References:

Keying, Wu;Lei, Tian;Hongye, Li;Jian, Li;Liqin, Chen [Journal of labelled compounds and radiopharmaceuticals,2009,vol. 52,# 13,p. 535 - 537] Location in patent:experimental part