![](/CAS/GIF/26060-06-0.gif)
2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE synthesis
- Product Name:2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE
- CAS Number:26060-06-0
- Molecular formula:C12H7NO2S
- Molecular Weight:229.25
![2-Thiophenecarbonyl chloride](/CAS/GIF/5271-67-0.gif)
5271-67-0
254 suppliers
$5.00/1g
![Anthranilic acid](/CAS/GIF/118-92-3.gif)
118-92-3
4 suppliers
$23.00/250g
![2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE](/CAS/GIF/26060-06-0.gif)
26060-06-0
23 suppliers
$28.60/5MG
Yield:26060-06-0 99%
Reaction Conditions:
with acetic anhydride;triethylamine in ethyl acetate;
Steps:
1 2-(2'-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE
Example 1 2-(2'-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE A solution of anthranilic acid (2.0 g, 15 mmol), 2-thienylcarbonyl chloride (2.2 g, 15 mmol), and triethylamine (1.5 g, 15 mmol) in ethyl acetate (9 mL) was stirred for 1 h. The solution was filtered and concentrated to a solid (3.7 g, 99%). The solid (1 g, 4 mmol) was heated at reflux with acetic anhydride (20 mL) for 18 h. The reaction mixture was concentrated, washed with water, and dried to give the title compound (0.92 g, 99%); m.p. 129-130° C.
References:
US5939421,1999,A
![2-Iodothiophene](/CAS/GIF/3437-95-4.gif)
3437-95-4
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$6.00/5g
201230-82-2
1 suppliers
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![2-Iodoaniline](/CAS/20180808/GIF/615-43-0.gif)
615-43-0
413 suppliers
$5.00/5g
![2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE](/CAS/GIF/26060-06-0.gif)
26060-06-0
23 suppliers
$28.60/5MG
![2-Ethynylthiophene](/CAS/GIF/4298-52-6.gif)
4298-52-6
154 suppliers
$24.00/1g
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![2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE](/CAS/GIF/26060-06-0.gif)
26060-06-0
23 suppliers
$28.60/5MG
![N-(2-acetylphenyl)-2-thiophenecarboxamide](/CAS/20180711/GIF/41242-35-7.gif)
41242-35-7
1 suppliers
inquiry
![2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE](/CAS/GIF/26060-06-0.gif)
26060-06-0
23 suppliers
$28.60/5MG
![2-Thiophenecarbonyl chloride](/CAS/GIF/5271-67-0.gif)
5271-67-0
254 suppliers
$5.00/1g
201230-82-2
1 suppliers
inquiry
![2-Iodoaniline](/CAS/20180808/GIF/615-43-0.gif)
615-43-0
413 suppliers
$5.00/5g
![2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE](/CAS/GIF/26060-06-0.gif)
26060-06-0
23 suppliers
$28.60/5MG