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2,3,4,5-tetramethylaniline synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: concentrated H2SO4; chloroform; HNO3 / 0 °C
2: tin; aqueous hydrochloric acid; acetic acid

References:

Smith;Horner [Journal of the American Chemical Society,1940,vol. 62,p. 1349,1353]