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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

2-(3,4-Dichlorophenyl)-3-hydroxyacrylonitrile synthesis

1synthesis methods
3218-49-3 Synthesis
3,4-Dichlorophenylacetonitrile

3218-49-3
255 suppliers
$5.00/5g

109-94-4 Synthesis
Ethyl formate

109-94-4
461 suppliers
$10.00/10g

2-(3,4-Dichlorophenyl)-3-hydroxyacrylonitrile

77186-41-5
9 suppliers
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Yield:77186-41-5 60%

Reaction Conditions:

with tert-Amyl alcohol;sodium hydride in toluene at 70 - 80; for 6 h;

References:

Selleri;Bruni;Costanzo;Guerrini;Casilli;Giusti;Lucacchini;Martini [Il Farmaco,1995,vol. 50,# 10,p. 679 - 687]