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ChemicalBook CAS DataBase List (2,3,5-TRIMETHYLPHENOXY)ACETIC ACID
74592-71-5

(2,3,5-TRIMETHYLPHENOXY)ACETIC ACID synthesis

3synthesis methods
-

Yield:74592-71-5 84%

Reaction Conditions:

Stage #1: 2,3,5-trimethylphenolwith sodium hydroxide in butanone at 50; for 1 h;
Stage #2: bromoacetic acid in butanone at 50; for 4 h;

References:

Wakabayashi, Takeshi;Tokunaga, Norihito;Tokumaru, Kazuyuki;Ohra, Taiichi;Koyama, Nobuyuki;Hayashi, Satoru;Yamada, Ryuji;Shirasaki, Mikio;Inui, Yoshitaka;Tsukamoto, Tetsuya [Journal of Medicinal Chemistry,2016,vol. 59,# 10,p. 5109 - 5114] Location in patent:supporting information