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2-(3-bromopropyl)Furan synthesis

4synthesis methods
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Yield:92513-83-2 58%

Reaction Conditions:

Stage #1: furanwith n-butyllithium in tetrahydrofuran at 0; for 1 h;Inert atmosphere;
Stage #2: 1,3-dibromo-propane in tetrahydrofuran at 20; for 12 h;Inert atmosphere;

References:

Mao, Jianyou;Liu, Feipeng;Wang, Min;Wu, Lin;Zheng, Bing;Liu, Shangzhong;Zhong, Jiangchun;Bian, Qinghua;Walsh, Patrick J. [Journal of the American Chemical Society,2014,vol. 136,# 50,p. 17662 - 17668] Location in patent:supporting information