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2-(3-chlorophenyl)acetyl chloride synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: aq. Ag2O / dioxane
2: (COCl)2; DMF / CH2Cl2

References:

Young, Jonathan R.;Huang, Song X.;Chen, Irene;Walsh, Thomas F.;DeVita, Robert J.;Wyvratt Jr., Matthew J.;Goulet, Mark T.;Ren, Ning;Lo, Jane;Yang, Yi Tien;Yudkovitz, Joel B.;Cheng, Kang;Smith, Roy G. [Bioorganic and Medicinal Chemistry Letters,2000,vol. 10,# 15,p. 1723 - 1727]