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ChemicalBook CAS DataBase List 2,3-Dibenzyl-5-broMobenzoic Acid Methyl Ester
182676-91-1

2,3-Dibenzyl-5-broMobenzoic Acid Methyl Ester synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 71 percent / Br2, HOAc / 20 h / Ambient temperature
2: 84 percent / H2SO4 / 16 h / Heating
3: 65 percent / NaH / dimethylformamide / 18 h / 0 deg C -> room temperature

References:

Yee, Nathan K.;Nummy, Larry J.;Roth, Gregory P. [Bioorganic and Medicinal Chemistry Letters,1996,vol. 6,# 19,p. 2279 - 2280]