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54928-74-4

2,3-dihydro-1-benzothiophen-6-amine synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 81 percent / H2 / Pd/C / 2-methoxy-ethanol / 4 h / 50 °C / 2625.2 Torr
2: 67 percent / DIBAL / hexane; dioxane / 5 h / 70 °C

References:

Sauter;Jordis;Tanyolac;Martinek [Archiv der Pharmazie,1988,vol. 321,# 4,p. 241 - 246]