Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

57413-40-8

2,3-dihydro-1-Methyl-1H-Indole-5-carbonitrile synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: BF3*OEt2 / xylene / 2 h / 145 °C
2.1: selenenyl bromide resin; SnCl4 / CH2Cl2 / 1 h / 0 °C
2.2: n-Bu3SnH; AIBN / toluene / 2 h / 90 °C

References:

Nicolaou;Roecker;Hughes, Robert;Van Summeren, Ruben;Pfefferkorn, Jeffrey A.;Winssinger, Nicolas [Bioorganic and Medicinal Chemistry,2003,vol. 11,# 3,p. 465 - 476]