2-(3-Methylbutyl)-2H-pyrazole-3-boronic acid synthesis
- Product Name:2-(3-Methylbutyl)-2H-pyrazole-3-boronic acid
- CAS Number:847818-66-0
- Molecular formula:C8H15BN2O2
- Molecular Weight:182.03
847818-51-3
10 suppliers
inquiry
847818-66-0
22 suppliers
$120.00/100mg
Yield:847818-66-0 63%
Reaction Conditions:
Stage #1: 1-(3-methylbutyl)-1H-pyrazolewith n-butyllithium in tetrahydrofuran;hexane at 5 - 20; for 1 h;
Stage #2: with Trimethyl borate in tetrahydrofuran;hexane at -70; for 0.5 h;
Stage #3: with ammonium chloride in tetrahydrofuran;hexane at -15 - 20; for 1 h;
References:
Ivachtchenko, Alexandre V.;Kravchenko, Dmitry V.;Zheludeva, Valentina I.;Pershin, Dmitry G. [Journal of Heterocyclic Chemistry,2004,vol. 41,# 6,p. 931 - 939]