2(3H)-Benzofuranone, 3-(hydroxymethylene)- synthesis
- Product Name:2(3H)-Benzofuranone, 3-(hydroxymethylene)-
- CAS Number:70450-82-7
- Molecular formula:C9H6O3
- Molecular Weight:162.14
Yield:70450-82-7 95%
Reaction Conditions:
with sodium methylate in N,N-dimethyl-formamide at 40; under 225023 Torr; for 6 h;Green chemistry;Reagent/catalyst;Solvent;Temperature;Pressure;
Steps:
1-4 Example 1
After adding 13.4g (BOF, 0.1mol) of benzofuran-2(3H)-one to 100ml DMF to dissolve it, add 6.8g of sodium methoxide (purity 97% by weight, 0.12mol),After the CO was introduced, the temperature was increased to 40°C, and the pressure of the CO was maintained at 30 MPa, and the reaction was conducted for 6 hours.Cool down and release pressure, and perform quantitative analysis on the reaction liquid,The measured yield of 3-hydroxymethylenebenzofuran-2(3H)-one (LS-MS[M+H]+=163) was 95%.
References:
CN113004234,2021,A Location in patent:Paragraph 0005; 0040-0045; 0047-0048
40800-90-6
44 suppliers
$155.00/100mg
70450-82-7
2 suppliers
inquiry