2-(4,4-Difluorocyclohexyl)acetonitrile synthesis
- Product Name:2-(4,4-Difluorocyclohexyl)acetonitrile
- CAS Number:959600-88-5
- Molecular formula:C8H11F2N
- Molecular Weight:159.18
Yield:959600-88-5 92%
Reaction Conditions:
in N,N-dimethyl-formamide;Reflux;
References:
Xin, Bo-Tao;Huber, Eva M.;De Bruin, Gerjan;Heinemeyer, Wolfgang;Maurits, Elmer;Espinal, Christofer;Du, Yimeng;Janssens, Marissa;Weyburne, Emily S.;Kisselev, Alexei F.;Florea, Bogdan I.;Driessen, Christoph;Van Der Marel, Gijsbert A.;Groll, Michael;Overkleeft, Herman S. [Journal of Medicinal Chemistry,2019,vol. 62,# 3,p. 1626 - 1642] Location in patent:supporting information
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