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1166378-32-0

2,4,7-trichloro-6-bromoquinazoline synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 3 h / 200 °C
2.1: trichlorophosphate / 48 h / Reflux
2.2: 0 °C

References:

ARAXES PHARMA LLC;LI, Liansheng;FENG, Jun;WU, Tao;REN, Pingda;LIU, Yi;LIU, Yuan;LONG, Yun, Oliver WO2015/54572, 2015, A1