2-(4-Chloro-phenoxymethyl)-1H-benzoimidazole synthesis
- Product Name:2-(4-Chloro-phenoxymethyl)-1H-benzoimidazole
- CAS Number:3156-18-1
- Molecular formula:C14H11ClN2O
- Molecular Weight:258.7
Yield:3156-18-1 80%
Reaction Conditions:
Stage #1: 4-chloro-phenolwith potassium carbonate in water;N,N-dimethyl-formamide; for 1 h;
Stage #2: 2-chloromethyl-1H-benzimidazolewith potassium iodide in water;N,N-dimethyl-formamide; for 6 h;Reflux;
References:
Ibrahim, Nasser A. [Egyptian Journal of Chemistry,2008,vol. 51,# 6,p. 823 - 836] Location in patent:experimental part
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