2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID synthesis

4synthesis methods

Product Name:2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID
CAS Number:117309-41-8
Molecular formula:C14H12ClNO4S
Molecular Weight:325.77

methyl 2-[(4-chlorophenyl)-phenylsulfonyl-amino]ethanoate

418806-66-3
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2-[4-CHLORO(PHENYLSULFONYL)ANILINO]ACETIC ACID

117309-41-8
20 suppliers
$45.00/50mg

Yield:117309-41-8 82.5 %

Reaction Conditions:

with sodium hydroxide in methanol at 20;

Steps:

1.3 (3) Synthesis of intermediates:

Put solid b1 (2.15g, 0.0063mol) in a 50mL eggplant-shaped bottle, add 20mL of methanol and stir to dissolve, add sodium hydroxide (0.51g, 0.0126mol), stir at room temperature for 1.5h, concentrate the reaction solution, add water and stir to dissolve the solid , filtered off the insoluble matter, the filtrate was adjusted to pH 2-3 with concentrated hydrochloric acid, and suction filtered to obtain a white solid c1, which weighed 1.69g after drying, and the yield was 82.5%

References:

CN115322126,2022,A Location in patent:Paragraph 0027; 0033-0034

4750-28-1 Synthesis

4750-28-1
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$90.00/1mg

117309-41-8
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$45.00/50mg

References

98-09-9
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$12.00/25g

117309-41-8
20 suppliers
$45.00/50mg

References

106-47-8 Synthesis

106-47-8
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$5.00/5G

117309-41-8
20 suppliers
$45.00/50mg

References