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2-[(4-methoxybenzyl)amino]isonicotinonitrile synthesis

2synthesis methods
3939-14-8 Synthesis
2-FLUOROISONICOTINONITRILE

3939-14-8
127 suppliers
$6.00/1g

2393-23-9 Synthesis
4-Methoxybenzylamine

2393-23-9
462 suppliers
$20.00/25g

2-[(4-methoxybenzyl)amino]isonicotinonitrile

618446-32-5
9 suppliers
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Yield:618446-32-5 87%

Reaction Conditions:

in N,N-dimethyl acetamide at 130; for 1 h;

References:

Green, Jeremy;Cao, Jingrong;Bandarage, Upul K.;Gao, Huai;Court, John;Marhefka, Craig;Jacobs, Marc;Taslimi, Paul;Newsome, David;Nakayama, Tomoko;Shah, Sundeep;Rodems, Steve [Journal of Medicinal Chemistry,2015,vol. 58,# 12,p. 5028 - 5037]