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ChemicalBook CAS DataBase List 2-(4-METHOXYPHENYL)THIAZOLE-5-CARBALDEHYDE

2-(4-METHOXYPHENYL)THIAZOLE-5-CARBALDEHYDE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium carbonate / triphenylphosphine; palladium diacetate / N,N-dimethyl-formamide; water / 3 h / 100 °C
2.1: n-butyllithium / hexane; tetrahydrofuran / -78 °C
2.2: 0 °C

References:

Daiichi Sankyo Company, Limited EP2308838, 2011, A1